Bioactive Folate as Quatrefolic®
5-MTHF, provided as Quatrefolic, is the most biologically active form of the water-soluble B vitamin, folic acid. It is the preferred form of folate supplementation due to an array of conditions that can limit conversion or absorption of folic acid. Data indicate that supplementing with 5-MTHF increases plasma folate more effectively than folic acid.*
![5-MTHF-60c_300000088_[HIRES]](https://www.drguberman.com/wp-content/uploads/2026/03/5-MTHF-60c_300000088_HIRES.png)




