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Cyrex Array 20 - Blood-Brain Barrier Permeability (Includes Doctor's Consultation on All Test Results)
Cyrex Array 20 - Blood-Brain Barrier Permeability (Includes Doctor's Consultation on All Test Results)
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Cyrex Labs-Array 20-Blood Brain Barrier
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525
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Description
Blood Brain Barrier Permeability
PRICE INCLUDES CONSULT WITH DR. GUBERMAN TO DISCUSS TEST RESULTS
OVERVIEW
The blood brain barrier (BBB) is a physical barrier between the brain and the circulating blood, formed by the arrangement of endothelial cells and tight junctions that line the capillaries, which supply blood to the brain. It is a highly selective barrier that restricts the movement of all soluble proteins greater than 400 Da from the blood across to the brain. Acting like a filter, the BBB protects the brain from infections, the products of infections such as lipopolysaccharides (LPS), and toxic chemicals, etc., that circulate in the blood. The BBB naturally permits the passage of essential metabolites, small hydrophobic (lipid soluble) molecules like oxygen, carbon-dioxide, hormones, etc
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Clinical Use:
Recommended for patients who:
• Early investigation in management of contact sports-related Traumatic Brain Injury (TBI).
• Evaluation of breach of the Blood-Brain Barrier by stress, trauma or environmental triggers, even in the absence of apparent concussion or brain injury.
• Assist in the assessment of increased risk of neurodegenerative disorders including, but not limited to, Multiple Sclerosis, Amyotrophic Lateral Sclerosis (Lou Gehrig’s Disease), Senile Dementia, Alzheimer’s Disease, Parkinson’s Disease, Epilepsy and Stroke.
• Play contact sports during which repeated head trauma occurs.
• Engage in activity that involves force or shock to the body and/or head.
• Have intestinal permeability with abnormal elevation in LPS and/or Occludin/Zonulin antibodies.
• Exhibit changes in cognitive function.
Here is what is tested:
Array 20 – Blood Brain Barrier Permeability
1.
Blood Brain Barrier Protein IgG + IgA combined ( CPT CODE : 83516 )
Array 20 – Blood Brain Barrier Permeability
2.
Blood Brain Barrier Protein IgM ( CPT CODE : 83516 )
Array 20 – Blood Brain Barrier Permeability
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