What Size Dose Is High Enough?
The RDI for magnesium is 400mg per day, so everyone should at least get that much.
Jigsaw Health's recommended dose is a little higher at 500mg a day (or more, as bowel tolerance allows). This is because many people have been running low on magnesium for years and need more than the "minimum" to replenish their magnesium stores.
Some experts in the field — such as Dr. Russell Blaylock — recommend 1000mg a day as the optimal dose to relieve the effects that can be connected to magnesium-deprived diets.*
Low Dose vs. High Dose Magnesium Supplements
Although there are thousands of cheaper magnesium supplements available, the simple truth is that you CANNOT replenish your body's magnesium stores with a cheap magnesium supplement.
Why? Because you cannot take high doses of a regular magnesium supplement without it causing a very uncomfortable laxative effect—your body's way of discarding high levels of magnesium that it is unable to absorb all at once. And the low doses you're restricted to simply won't deliver results.
So, yes other magnesium supplements cost less, but that doesn't matter much when the ONLY thing they will deliver — at high enough doses — is an extreme laxative effect.
Our SRT technology successfully addresses this issue by SLOWLY releasing a higher amount of magnesium, pacing it out over 6 to 8 hours—a rate at which your body can properly absorb and utilize the mineral. Your body gets the magnesium it's craving, without any digestive drama.*
What is Quatrefolic®?
Quatrefolic® (5-MTHF, or folate) is an active form of Vitamin B-9, folic acid. For many people, it is difficult to convert folic acid into folate.
Folate is an important co-factor to P5P and beneficial to many bodily functions. Together, these greatly improve Magnesium’s function supporting healthy muscular tone, enhancing overall energy, and promoting stable mood, calmness, and good sleep.
Why is Vitamin B6 (Pyridoxal-5-Phosphate) included?
P5P (Pyridoxal-5-Phosphate), the active form of Vitamin B6, performs over 30 critical enzymatic reactions in the body, including the manufacture of serotonin and dopamine in the brain. The inactive forms of B6 (pyridoxine hydro-chloride, pyridoxal, or pyridoxamine) have to be converted by the liver to the active form (Pyridoxal-5-Phosphate or P5P) the body needs. Individuals with compromised liver function have difficulty making this conversion and consequently may be at risk of a vitamin B6 deficiency.
P5P works synergistically with Magnesium in many kinds of ways, including relaxing muscles and nerves. A deficiency in either causes many issues where the body depends on both Mg and P5P. We put them together because it is not unusual for people with chronic illness to not make P5P effectively. It is critical to get both.
Since Vitamin B6 is already difficult to get and convert into its usable form, we give it to you already in its active P5P form. All the benefits are available immediately after absorption - no trouble converting or waiting.
Why is Vitamin B12 (Methylcobalamin) included?
Methylcobalamin, the active form of Vitamin B12, is included as a supporting B vitamin to contribute to the effectiveness of Magnesium.
Additionally, methylcobalamin is a necessary cofactor for your body's ability to properly methylate. Methylation is a cycle that occurs in your body billions of times every second. It's one of the most important biochemical processes for long-term health and essential for the proper function of almost all of your body's systems.
Using the active form of B12 is particularly important because people with chronic conditions are poor methylators -- making it difficult to convert inactive forms into their useful active form.
Furthermore... Mangesium, B6, B9, and B12 work together to help maintain normal blood levels of the amino acid, homocyteine.
Homocysteine at high concentrations is linked to serious health conditions. Magnesium and these supporting B vitamins work together to maintain normal blood levels for optimal health.