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Meda-Stim supplies vitamins, minerals, amino acids, and botanical constituents to support the normal conversion of thyroid hormones, T-4 to T-3. In the bloodstream, T3 and T4 are carried by thyroine-binding globulin, thyroxine binding preablumin and serum albumin. T4 is converted to T3 by the liver, lungs, kidneys and heart by a selenium-dependent enzyme called Iodothyronine-5 monodeiodinase. T3 is then taken up by appropriate target cells, where it is transported to the nucleus to activate transcription.