In a clinical study of postmenopausal women with low estrogen levels, Ostera™—in conjunction with a modified Mediterranean, low glycemic diet and regular exercise—was shown to beneficially influence key markers of bone remodeling more than diet and exercise alone. Bone remodeling is the natural process of healthy breakdown and formation of the bone matrix—the structure where minerals are deposited. This scientifically advanced formula features selective kinase response modulators (SKRMs) in the form of RIAA, as well as the herb berberine, and vitamins D and K to nutritionally support healthy bone remodeling during the aging process. Recommended for use with Cal Apatite®â€”an advanced bioactive formulation for bone mineralization.*