Study Results from Arizona State University Update Understanding of Clinical Trials and Studies [Vitamin D Supplementation Appears to Increase Plasma A beta(40) in Vitamin D Insufficient Older Adults: A Pilot Randomized Controlled Trial]
By a News Reporter-Staff News Editor at Clinical Trials Week -- Current study results on Clinical Research have been published. According to news originating from Phoenix, Arizona, by NewsRx correspondents, research stated, "Low plasma amyloid-beta (A beta) is linked to Alzheimer's disease. Since vitamin D cleared brain A beta in vitro, this 8-week trial examined whether vitamin D increased plasma A beta(40)."
Our news journalists obtained a quote from the research from Arizona State University, "Vitamin D insufficient adults (6/18 M/F; 64.3 +/- 10.9 y) were randomized to placebo or vitamin (50,000 IU/week) treatments. The vitamin group experienced greater plasma A beta(40) change than controls, + 14.9 +/- 12.0 and + 12.8 +/- 12.8 pg/mL (p = 0.045; effect size, 0.228). Change in A beta(40) for older participants (>= 60 y) was + 18.3 +/- 33.6 and -3.2 +/- 44.5 pg/mL for vitamin (n = 4) and placebo (n = 4) groups (effect size, 0.295)."
According to the news editors, the research concluded: "Thus, vitamin D may increase plasma A beta, particularly in older adults, suggesting decreased brain A beta."
For more information on this research see: Vitamin D Supplementation Appears to Increase Plasma A beta(40) in Vitamin D Insufficient Older Adults: A Pilot Randomized Controlled Trial. Journal of Alzheimers Disease, 2016;52(3):843-847. Journal of Alzheimers Disease can be contacted at: Ios Press, Nieuwe Hemweg 6B, 1013 Bg Amsterdam, Netherlands (see also Clinical Research).