1. Toxigenic C. difficile Culture, stool

Toxigenic C. difficile Culture, stool

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This specific anaerobic culture identifies C. difficile, which is often present in healthy individuals, but can be associated with antibiotic-associated diarrhea. If C. difficile is cultured at any level, the sample is automatically tested for all known toxigenic strains using an FDA-cleared, molecular diagnostic DNA assay at no additional charge.

This test is useful for

  • Antibiotic-Associated Diarrhea
  • Autism Spectrum Disorders

Detailed Information

Clostridia are anaerobic Gram-positive bacteria that do not grow in the more aerobic environment of the distal colon. However Clostridia produce extremely durable endospores as a means of proliferation—the spores are resistant to air, antibiotics, heat, drying and disinfectants. For this test, Doctor's Data uses growth media optimally suited for growth of Clostridium difficile and anaerobic culture conditions to germinate the spores to metabolically active bacteria that are sub-cultured for positive identification (speciation). If C. difficile is cultured at any level, the sample is automatically tested for all known toxigenic strains using an FDA-cleared, molecular diagnostic DNA assay at no additional charge. Clostridia generally are resistant to antibiotics and treatment of an overgrowth of C. difficile, especially in asymptomatic carriers and infants under age two, is usually not warranted. Additionally, since plasmids have a potential role in transferring various capacities, including antibiotic resistance, from one organism to another, the use of antibiotics in the treatment of clostridia overgrowth should be considered carefully.


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