MUCOSAL IMMUNE REACTIVITY SCREEN:
PRICE INCLUDES CONSULT WITH DR. GUBERMAN TO DISCUSS TEST RESULTS
There are two major mechanisms of protection in the body, both of which defend against foreign materials: • Mucosal immune system • Circulatory or systemic immune system Both systems are independent of one another but have the capability to communicate with each other.
A. The mucosal immune system is the first line of defense that protects our body against the variety of antigens that comes in contact with the human body. Normally, these antigens are originated from the environment, oral cavity, lungs, and gastrointestinal (GI) tract. This system’s major antibody isotype is IgA, which plays an important role in the elimination of food and bacterial antigens from the GI tract. The secondary antibody isotype is IgM, which, in individuals with IgA deficiency, compensates for the decrease in IgA function.
B. The circulatory or systemic immune system produces IgG, IgM and IgA isotype antibodies against antigens that come in contact with macrophages or antigen-presenting cells. Under certain conditions, for example, immune dysregulation, the body may produce IgE antibody, which is responsible for the prevention of parasitic infection or the induction of allergic reactions.
| CLINICAL USE: |
RECOMMENDED FOR PATIENTS WHO: |
Evaluate mechanisms of compromised immune tolerance.
Evaluate possible outcomes of compromised mucosal tolerance, such as: intestinal barrier dysfunction, food and chemical immune reactivity, and autoimmunity |
Have chronic inflammatory bowel conditions.
Have a family history of autoimmune disease. |
WHAT WE TEST FOR
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| 1. |
Total Secretory IgA ( CPT CODE : 83516 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 2. |
Lipopolysaccharides ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 3. |
Occludin/Zonulin ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 4. |
Actomyosin ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 5. |
ASCA/ANCA ( CPT CODE : 83516 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 6. |
Calprotectin ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 7. |
Alpha-Gliadin ( CPT CODE : 83516 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 8. |
Gamma-Gliadin ( CPT CODE : 83516 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 9. |
Glutenin ( CPT CODE : 83516 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 10. |
Gluteomorphin ( CPT CODE : 83516 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 11. |
Wheat Germ Agglutinin ( CPT CODE : 83516 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 12. |
Transglutaminase-2 ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 13. |
Egg ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 14. |
Soy ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 15. |
Corn ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 16. |
Alpha + Beta Casein ( CPT CODE : 83516 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 17. |
Casomorphin ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 18. |
Aflatoxin ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 19. |
Bisphenol-A ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 20. |
Mercury ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 21. |
Mixed Heavy Metals ( CPT CODE : 86256 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 22. |
Rotavirus ( CPT CODE : 83516 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 23. |
Myelin Basic Protein ( CPT CODE : 83516 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 24. |
Blood-Brain Barrier Protein ( CPT CODE : 83516 )
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Array 14 – Mucosal Immune Reactivity Screen
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| 25. |
Immune Complex ( CPT CODE : 86332 )
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Array 14 – Mucosal Immune Reactivity Screen
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